Abso-fucking-lutely!
I've actually had problems lately and been reading a lot of YA series, because it kind of depresses me. I'm in my 20s, but in no way have my life "together" yet, and even the protagonists I can think of who are under 30 outside of YA are in some kind of crazy-world where they can afford stuff like houses, health insurance, have successful 9-5 jobs where they've been working for several years, etc. They feel like they're physically attractive versions of my mom. I still love reading about them, but it would be cool to get that in the middle age group going.

It's especially weird to me since I'm a big fan of manga, and that age group is pretty well represented there. I'm thinking of stories like NANA or chobits, where the protagonist has a first apartment, is trying to figure out how to find a job that doesn't bore them senseless and still pays their bills, etc.

It's kind of weird sometimes, because I see a lot of YA books where the author is basically making the characters "pseudo college" in some way... they have an apartment of their own or with people their own age, are in high school but never seem to go to class, or they have a job. it would open up a lot of nifty stories if that age group got more fiction, and help to make a lot more things more believable.