One interesting thing to me is that many teetotallers (I used to be one, but now I drink a glass of wine occasionally, maybe once a week on average) have a completely false concept of wine. One serving of alcohol does not impair you at all. A glass of wine drunk with a meal won't even be something you "feel" in the least (unless you have an unusual sensitivity to it), and having a very slight reaction to alcohol is not biblical drunkeness. (I had a very slight buzz once, to homemade wine that the makers had accidentally made way too strong. I would not have driven anywhere for an hour or so after drinking it, but I was fully able to walk around and engage in intelligent conversation.)

Scripture never says that drinking wine is a sin. It's fine to choose not to drink, just as it is fine to choose not to marry. But neither abstaining from marriage nor abstaining from wine is more "holy" than accepting God's gift, nor more likely to impress the unbeliever.